Function-oriented investigations of a peptide-based catalyst that mediates enantioselective allylic alcohol epoxidation.
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چکیده
منابع مشابه
Function-Oriented Investigations of a Peptide-Based Catalyst that Mediates Enantioselective Allylic Alcohol Epoxidation.
We detail an investigation of a peptide-based catalyst 6 that is effective for the site- (>100:1:1) and enantioselective epoxidation (86% ee) of farnesol. Studies of the substrate scope exhibited by the catalyst are included, along with an exploration of optimized reaction conditions. Mechanistic studies are reported, including relative rate determinations for the catalyst and propionic acid, a...
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ژورنال
عنوان ژورنال: Chem. Sci.
سال: 2014
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c4sc01440e